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Dead by Monday is a darkly comic tale of love and death... but not necessarily in that order. Julie is a sweet, vulnerable young woman who lacks confidence and is obsessed with the memory of her dead husband whom she idealizes. Alex is an angry writer. Talented but unable to repeat the success of his first novel, he has nothing left to say. Or live for. He just wants to die. Fate introduces these two lost souls at the edge of a cliff. While picking flowers Julie accidentally falls off. Alex, who has come to blow his brains out, is interrupted by her cry for help, just before he pulls the trigger.

Hard-drinking novelist Zach Hutton spirals out of control after his wife and mistress both leave him. Alone and crippled by a bad case of writer's block, Zach slips in and out of casual relationships and one-night stands, while his drinking becomes more and more severe. With the help of a bartender and his therapist, Zach confronts his demons — women and alcohol.

Larry Donner, an author with a cruel ex-wife, teaches a writing workshop in which one of his students, Owen, is fed up with his domineering mother. When Owen watches a Hitchcock classic that seems to mirror his own life, he decides to put the movie's plot into action and offers to kill Larry's ex-wife, if Larry promises to murder his mom. Before Larry gets a chance to react to the plan, it seems that Owen has already set things in motion.

Charlie Kaufman is a confused L.A. screenwriter overwhelmed by feelings of inadequacy, sexual frustration, self-loathing, and by the screenwriting ambitions of his freeloading twin brother Donald. While struggling to adapt "The Orchid Thief," by Susan Orlean, Kaufman's life spins from pathetic to bizarre. The lives of Kaufman, Orlean's book, become strangely intertwined as each one's search for passion collides with the others'.

The adventures of a father and his young daughter, in their search for a long lost book that will help reunite a missing, close relative.

A young director intent on making "the greatest color crime movie ever" can't seem to finish his script-he has a beginning and an end, but he can't quite figure out the middle. The daughter of his landlord, excited to have a real "movie person" living nearby, tries to help by putting him in touch with a man who wants to collaborate on a script-the strange "Dr. Jolly"

It sounds like a budding writer's dream: a bestselling first novel, a luxurious house in Malibu, and a trophy wife... But it all unravels when writer's block and a failed marriage send Richard McMurray out into the streets.

Writer Alex Sheldon must finish his novel within a month. If he doesn't, he won't get paid. And, if that happens, angry Mafia types to whom he owes money will come looking for him. In order to expedite things, Alex hires typist Emma Dinsmore and begins dictating his novel. The book is about a doomed love affair between a character similar to Alex and a character named Polina Delacroix. But, as Alex falls for Emma, his work takes a different turn.

Writer Harry Block draws inspiration from people he knows, and from events that happened to him, sometimes causing these people to become alienated from him as a result.

Harold Crick is a lonely IRS agent whose mundane existence is transformed when he hears a mysterious voice narrating his life.

On Christmas Eve, suffering from a case of writer's block, screenwriter Mark Christopher and his gofer Virgil get an unexpected visit from Sergeant Maizel. Knowing Christopher is working on a juvenile delinquent script, the sergeant brings by delinquent Susan thinking she will inspire Christopher while providing a place for her to spend the holidays outside of juvenile hall.