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Two sisters embark on a hilarious, mile-a-minute road trip to rescue their grandmother and her beloved dog from her retirement home before their reckless sister gets there first.

A reformed criminal's attempt at going straight is derailed when he reunites with his sanity-testing twin brother on a road trip for the score of a lifetime. Dodging bullets, the law, and an overbearing mother along the way, they must heal their severed family bond before they end up killing each other.

Trucker Rubber Duck and his buddies Pig Pen, Widow Woman and Spider Mike use their CB radios to warn one another of the presence of cops. But conniving Sheriff Wallace is hip to the truckers' tactics, and begins tricking the drivers through his own CB broadcasts. Facing constant harassment from the law, Rubber Duck and his pals use their radios to coordinate a vast convoy and rule the road.

Two middle-aged men embark on a spiritual journey through Californian wine country. One is an unpublished novelist suffering from depression, and the other is only days away from walking down the aisle.

Jake Blues, just released from prison, puts his old band back together to save the Catholic home where he and his brother Elwood were raised.

Lightning McQueen, a hotshot rookie race car driven to succeed, discovers that life is about the journey, not the finish line, when he finds himself unexpectedly detoured in the sleepy Route 66 town of Radiator Springs. On route across the country to the big Piston Cup Championship in California to compete against two seasoned pros, McQueen gets to know the town's offbeat characters.

Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

An irritable marketing executive, Neal Page, is heading home to Chicago for Thanksgiving when a number of delays force him to travel with a well meaning but overbearing shower curtain ring salesman, Del Griffith.

Eleven-year-old Alexander and his family embark on a dream Spring Break vacation to Mexico City only to have all their plans go terribly wrong when they discover a cursed idol.

Corporate billionaire Edward Cole and working class mechanic Carter Chambers are worlds apart. At a crossroads in their lives, they share a hospital room and discover they have two things in common: a desire to spend the time they have left doing everything they ever wanted to do and an unrealized need to come to terms with who they are. Together they embark on the road trip of a lifetime, becoming friends along the way and learning to live life to the fullest, with insight and humor.

When Erik Stifler realizes that he's the only Stifler family member who might graduate high school a virgin, he decides to live up to his legacy. After some well-meaning advice from Jim's dad, Erik's ready to take his chances at the annual and infamous Naked Mile race, where his devoted friends and some uninhibited sorority girls will create the most outrageous weekend ever.