A writer for a radio program needs some fresh ideas to juice up his show. For inspiration, he rents a room with a typical American family and begins to secretly write about their true life antics. The show becomes a big hit, but he begins to feel guilty about his charade when he falls in love with the family's pretty older daughter.
Writer Harry Block draws inspiration from people he knows, and from events that happened to him, sometimes causing these people to become alienated from him as a result.
An insurance investigator begins discovering the impact a horror writer's books has on his fans is more than inspirational.
Blank-faced bug killer Bill Lee and his dead-eyed wife, Joan, like to get high on Bill's pest poisons while lounging with Beat poet pals. After meeting the devilish Dr. Benway, Bill gets a drug made from a centipede. Upon indulging, he accidentally kills Joan, takes orders from his typewriter-turned-cockroach, ends up in a constantly mutating Mediterranean city and learns that his hip friends have published his work - which he doesn't remember writing.
Near a gray and unnamed city is the Zone, a place guarded by barbed wire and soldiers, and where the normal laws of physics are victim to frequent anomalies. A stalker guides two men into the Zone, specifically to an area in which deep-seated desires are granted.
Charlie Kaufman is a confused L.A. screenwriter overwhelmed by feelings of inadequacy, sexual frustration, self-loathing, and by the screenwriting ambitions of his freeloading twin brother Donald. While struggling to adapt "The Orchid Thief," by Susan Orlean, Kaufman's life spins from pathetic to bizarre. The lives of Kaufman, Orlean's book, become strangely intertwined as each one's search for passion collides with the others'.
A writer attempts to raise some cash by writing a book about the Loch Ness Monster. No publisher will take it because they all think there isn't really a monster. The writer and some of his friends make a fake monster and take photographs and then travel to Scotland to see if they can convince the locals.
A Pulitzer-winning writer grapples with being a widower and father after a mental breakdown, while, 27 years later, his grown daughter struggles to forge connections of her own.
Holly Golightly is an eccentric New York City playgirl determined to marry a Brazilian millionaire. But when young writer Paul Varjak moves into her apartment building, her past threatens to get in their way.
Mortimer Brewster, a newspaper drama critic, playwright, and author known for his diatribes against marriage, suddenly falls in love and gets married; but when he makes a quick trip home to tell his two maiden aunts, he finds out his aunts' hobby - killing lonely old men and burying them in the cellar!
Fresh out of university, a Turkish young man with literary aspirations returns to his home village, and to his father, a debt-ridden man with a gambling problem.