In the seedy part of Los Angeles, a man who writes poetry has spent six months without leaving his apartment because of his paranoid delusions involving sadistic doctors, rappers, and spiders. A woman who seems to jinx things by wanting to help is dumped by her boyfriend and finds herself penniless on the streets, and soon runs afoul of a local gang. Due to a telephone glitch, the man calls her at a phone booth trying to dial a "talk line" and invites her to his place. There they must help each other to overcome their respective problems.
A hardened CIA operative finds himself at the mercy of a precocious 9-year-old girl, having been sent undercover to surveil her family.
An airline pilot and his wife are forced to face the consequences of her alcoholism when her addictions threaten her life and their daughter's safety. While the woman enters detox, her husband must face the truth of his enabling behavior.
When Manny Singer's wife dies, his young daughter Molly becomes mute and withdrawn. To help cope with looking after Molly, he hires sassy housekeeper Corrina Washington, who coaxes Molly out of her shell and shows father and daughter a whole new way of life. Manny and Corrina's friendship delights Molly and enrages the other townspeople.
Alex, Marty, and other zoo animals find a way to escape from Madagascar when the penguins reassemble a wrecked airplane. The precariously repaired craft stays airborne just long enough to make it to the African continent. There the New Yorkers encounter members of their own species for the first time. Africa proves to be a wild place, but Alex and company wonder if it is better than their Central Park home.
When an alien takes the form of a young widow's husband and asks her to drive him from Wisconsin to Arizona, the government tries to stop them.
Two middle-aged men embark on a spiritual journey through Californian wine country. One is an unpublished novelist suffering from depression, and the other is only days away from walking down the aisle.
With a reputation for seducing members of the opposite sex, regardless of their marital status, a notorious womanizer discovers a beauty who seems impervious to his charms. However, as he continues to pursue the indifferent lady, he finds himself falling in love.
In a world governed by commerce, Ricky and Kate, dedicated employees, find their lives forever changed when they encounter the enigmatic stranger G. As they navigate the realm of commerce, their paths intertwine in a surreal dance of love, loss, and redemption. G's presence, amplified through the pervasive influence of globalized television, casts a spell that reverberates beyond Ricky and Kate, impacting the lives of those who bear witness to their intertwined destinies.
On the verge of bankruptcy and desperate for his big break, aspiring filmmaker Bobby Bowfinger concocts a crazy plan to make his ultimate dream movie. Rallying a ragtag team that includes a starry-eyed ingenue, a has-been diva and a film studio gofer, he sets out to shoot a blockbuster featuring the biggest star in Hollywood, Kit Ramsey - only without letting Ramsey know he's in the picture.
When Ben Wrightman, a young teacher, begins dating pretty businesswoman Lindsey Meeks, the two don't seem to have a lot of the same interests, but they fall in love, regardless. Their romance goes well until baseball season begins, and Lindsey soon realizes that Ben is completely obsessed with the Boston Red Sox. Though she tries to understand Ben's passionate team loyalty, eventually it threatens to end their otherwise happy relationship.