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When actress Sarah Marshall dumps aspiring musician Peter Bretter for rock star Aldous Snow, Peter's world comes crashing down. His best friend Brian suggests that Peter should get away from everything and to fly off to Hawaii to escape all his problems. After arriving in Hawaii and meeting the beautiful receptionist Rachel Jansen, Peter is shocked to see not only Aldous in Hawaii, but also Sarah.

London publicist Helen, effortlessly slides between parallel storylines that show what happens when she does or does not catch a train back to her apartment. Love. Romantic entanglements. Deception. Trust. Friendship. Comedy. All come into focus as the two stories shift back and forth, overlap and surprisingly converge.

As the devoutly single Don Johnston is dumped by his latest girlfriend, he receives an anonymous pink letter informing him that he has a son who may be looking for him.

After standing in as best man for his longtime friend Carl Petersen, Randy Dupree loses his job, becomes a barfly and attaches himself to the newlywed couple almost permanently - as their houseguest. But the longer Dupree camps out on their couch, the closer he gets to Carl's bride, Molly, leaving the frustrated groom wondering when his pal will be moving out.

Five years after their summer together in Barcelona, Xavier, William, Wendy, Martine and Isabelle reunite.

With high school a distant memory, Jim and Michelle are getting married — and in a hurry, since Jim's grandmother is sick and wants to see him walk down the aisle — prompting Stifler to throw the ultimate bachelor party. And Jim's dad is reliable as ever, doling out advice no one wants to hear.

A group of young adults in their twenties, who share an apartment in the city of Seattle, ponder on love and face all the challenges of adulthood.

Two melancholic Hong Kong policemen fall in love: one with a mysterious underworld figure, the other with a beautiful and ethereal server at a late-night restaurant.

Mickey, a free-spirited New York cabbie, and Francis, a materialistic Wall Street stockbroker, are extremely competitive and confused about women as a result of their father's influence. Though they disagree about everything, they have one thing in common: Mickey's ex-fiance Heather is Francis's secret love. Though both brothers have beautiful wives, Heather triggers their longtime sibling rivalry

In 1970s Germany, Léopold, a 50-year-old businessman, picks up and seduces 20-year-old Franz, who swiftly moves into his apartment. The dynamic between them intensifies with the sudden arrival of their ex-girlfriends.

John Winger, an indolent sad sack in his 30s, impulsively joins the US Army after losing his job, his girlfriend and his apartment.