Cromossomo 21

In the beginning of the 19th century, Johannes Elias Alder is born in a small village in the Austrian mountains. While growing up he is considered strange by the other villagers and discovers his love of music, especially rebuilding and playing the organ at the village church. After experiencing an "acoustic wonder", his eye color changes and he can hear even the most subtle sounds.

The story of two kids, Kaew and Tong who catch a bus to Bangkok while escaping a rowdy boy who tries to bully Tong. The two innocent kids heading to the big city without knowing what they'll have to face in the future. When they step out from the bus, the adventure is about to begin.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

Amanda is reluctantly tasked with taking care of her new classmate, Lars, who has Down syndrome. To her surprise, Amanda and Lars develop a unique friendship. But in her struggle to fit in, Amanda ends up betraying Lars. Can Amanda find the courage to stand out and be true to herself?

During a blizzard in 1964, Dr. David Henry delivers his son Paul with the help of nurse Caroline. But when Henry realizes his wife is also carrying a girl with Down syndrome, he hands the second child over to Caroline without his wife's knowledge. Henry's fateful decision yields grave consequences for his family over the next 20 years.

Set in the neurosurgical ward of Copenhagen's Rigshospitalet, the city and country's main hospital, nicknamed "Riget", a number of characters, staff and patients alike, encounter bizarre phenomena, both human and supernatural.

Emma's daughter Kendall becomes engaged, but Emma is concerned as Kendall and her fiancé have Down Syndrome and Emma worries she's not ready to take this step.

A father fears the sexual awakening of his disabled son, a teenager living with Down syndrome, and struggles with the notion of letting him grow up.

Georges has Down syndrome, living at a mental-institution, Harry is a busy businessman, giving lectures for young aspiring salesmen. He is successful in his business life, but his social life is a disaster since his wife left him and took their two children with her. This weekend his children came by train to meet him, but Harry, working as always, forgot to pick them up. Neither his wife or his children want to see him again and he is driving around on the country roads, anguished and angry. He almost runs over Georges, on the run from the institution since everybody else went home with their parents except him, whose mother is dead. Harry tries to get rid of Georges but he won't leave his new friend. Eventually a special friendship forms between the two of them, a friendship which makes Harry a different person.

When Sam splits up with her partner, she is forced to move back into her childhood home with her mother and neurodivergent brother. When depression sinks in, her brother Emmett gets in her face trying to cheer her up and in doing so makes everything worse. But when Emmett is confronted with a situation at a baseball game where he is called a chicken, Sam rises to the challenge to come to his aid and is reminded of what is truly important.

In 1994, two brothers are enjoying the summer that will change everything: the youngest, Lucas, is starting school and will have to accept that his older brother, Bruno, who has Down syndrome, will not take part on this new adventure.