Murder, She Wrote: South by Southwest

A man ventures out into the streets of a pandemic-ridden London.

A street-wise kid, Mark Sway, sees the suicide of Jerome Clifford, a prominent Louisiana lawyer, whose current client is Barry 'The Blade' Muldano, a Mafia hit-man. Before Jerome shoots himself, he tells Mark where the body of a Senator is buried. Clifford shoots himself and Mark is found at the scene, and both the FBI and the Mafia quickly realize that Mark probably knows more than he says.

Six people travel by train overnight from Marseilles to Paris. When the train arrives at its destination, one of the passengers, a girl, is found dead in a sleeping berth. The police led by Inspector Grazzi investigate the other five passengers, suspecting that one of them was responsible. However, as the investigation is stepped up, the other passengers start turning up dead. It is then up to the last remaining two to solve the case, before they become the next victims.

Agatha Christie's classic whodunit speeds into the twenty-first century. World-famous sleuth Hercule Poirot has just finished a case in Istanbul and is returning home to London onboard the luxurious Orient Express. But, the train comes to a sudden halt when a rock slide blocks the tracks ahead. And all the thrills of riding the famous train come to a halt when a man discovered dead in his compartment, stabbed nine times. The train is stranded. No one has gotten on or gotten off. That can only mean one thing: the killer is onboard, and it is up to Hercule Poirot to find him.

Trapped in a London subway station, a woman who's being pursued by a potential attacker heads into the unknown labyrinth of tunnels beneath the city's streets

At the height of the frontier era, a train races through the Rocky Mountains on a classified mission to a remote army post. But one by one the passengers are being murdered, and their only hope is the mysterious John Deakin, who's being transported to face trial for murder.

When the daughter of a psychiatrist is kidnapped, he is horrified to discover that the abductors' demand is that he break through to a young woman, suffering from PTSD, who knows a secret six digit code number.

U.S. Marshall John Kruger erases the identities of people enrolled in the Witness Protection Program. His current assignment is to protect Lee Cullen, who's uncovered evidence that the weapons manufacturer she works for has been selling to terrorist groups. When Kruger discovers that there's a corrupt agent within the program, he must guard his own life while trying to protect Lee's.

After FBI agent Frank Lacrosse believes his son was kidnapped by a notorious serial killer, he travels to Amarillo, Texas, where he believes the murderer is in hiding. Although officially taken off the case because of its personal significance to him, Frank continues to pursue the killer, causing concern for local sheriff Buck Olmstead. When another victim pops up at a nearby car garage, Frank knows that he is as close as he'll ever be to tracking down the elusive killer.

A Chinese Department of Health junior clerk Su Zhenghuai is with his eldest daughter Su Wei and son Su Yuexuan are on their way to visit relatives in the provincial city when they meet the long-lost second daughter Su Ling. Unfortunately, the train is attacked by rats. Su Yuexuan is bitten by a rat and goes into a coma. In order to save his young son and many bitten passengers, Su Zhenghuai and Su Wei decide to make the dangerous venture to Xiaobaihe Hospital to get medicine.

Sadistic killer-for-hire Philip Raven becomes enraged when his latest job is paid off in marked bills. Vowing to track down his double-crossing boss, nightclub executive Gates, Raven sits beside Gates' lovely new employee, Ellen, on a train out of town. Although Ellen is engaged to marry the police lieutenant who's hunting down Raven, she decides to try and set the misguided hit man straight as he hides from the cops and plots his revenge.