Jason Crockett is an aging, grumpy, physically disabled millionaire who invites his family to his island estate for his birthday celebration. Pickett Smith is a free-lance photographer who is doing a pollution layout for an ecology magazine. Jason Crockett hates nature, poisoning anything that crawls on his property. On the night of his birthday the frogs and other members of nature begin to pay Crockett back.
Genetically-engineered Komodo dragons have become ginormous creatures hunting people on a remote tropical island. A small group of scientists must stop the dragons before they escape the island and destroy the rest of the world.
A nature field researcher is investigating the strange extinction of small animals and insects in the area, which indicates that something is wrong. His suspicions are soon to be proven right when he meets May, who lives in a cabin in the forest nearby. May says that her house is infested by small creatures that she thinks are mice or rats. When the couple search the house further, they notice that they're not rodents or insects. They are fast evolving lizards that have the appetite for animals and humans, no matter what size their prey are...
A group of geologists is attacked by gecko fiends that possess them, transforming them into zombies. Kwan travels there to give lectures and is possessed by the evil gecko spirit, However, her skeptical boyfriend doctor doesn't understand what's happening to her.
After exposure to radiation, an atomic research scientist finds himself changing into a murderous, lizard-like creature every time he is exposed to sunlight.
A group of passionate filmmakers venture deep into the mysterious underground Banning Tunnels, where they discover a lost city of cannibalistic, half-human, half-lizards.
A young suitor loses his girlfriend to a wealthy businessman. At first he's angry. Then in a fit of depression, he goes to the sea shore where he finds lizards. Immediately he puts the lizards into a bag and takes them home. Then he becomes obsessed with ladies dirty underwear and he steals six or seven "tainted" ones from public restrooms and brothels. At this point the man mixes the juices from the underwear with a special "aggressive compound" and then injects the fluid into the lizards. The little reptiles (now hooked on "love juice") become soldiers in his personal battle against females. "I hate women!" he screams, holding helpless victim's legs apart allowing the little creatures to gain entrance. Lots of women die, driven mad with sexual ecstasy and pain, while the misogynist psycho howls with laughter.
When a group of students search for mythical house lizards, one is bitten and becomes possessed. Now he's not only able to control the lizards but he finds himself transforming into one as well.
Primatologist Davis Okoye shares an unshakable bond with George, the extraordinarily intelligent, silverback gorilla who has been in his care since birth. But a rogue genetic experiment gone awry mutates this gentle ape into a raging creature of enormous size. To make matters worse, it’s soon discovered there are other similarly altered animals. As these newly created alpha predators tear across North America, destroying everything in their path, Okoye teams with a discredited genetic engineer to secure an antidote, fighting his way through an ever-changing battlefield, not only to halt a global catastrophe but to save the fearsome creature that was once his friend.
The tragic tale of two unlucky amphibians and a series of escalating blunders that ends their flirting for good.